THE Alli Source - Thin Diet Pill

How does Orlistat (Xenecol) work? Does it ihibit the digestive enzymes that would break down the fat?

I know this is random, but i have been given Orlistat and have just done about enzymes in biology. So my brain is now working overtime and i thought that maybe the orlistat is an inhibitor and this is why the fat comes out whole? Ooooh i love that i know how things work lol!! SO is it a non competitive inhibitor?

Public Comments

1. Orlistat binds to the enzyme lipase so that it can't break down the fat it would otherwise be working on. The fat then passes through the gut unprocessed and is passed out with faeces.
2. Orlistat is a lipase inhibitor, and it works by reducing the absorption of dietary fat. It is used in conjunction with a mildly hypocaloric diet in individuals with a body mass index (BMI) of 30 kg/m2 or more or in individuals with a BMI of 28 kg/m2 in the presence of other risk factors such as type 2 diabetes, hypertension, or hypercholesterolaemia. It may however impair absorption of fat-soluble vitamins. Hope this helps.